GATAD2B

Across TCGA patient cohorts, GATAD2B mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GATAD2B-associated genes across cancer lineages are ATM, Caspase-7-cleavedD198, and 14-3-3_beta. Each is linked with GATAD2B in more than 1 cancer types. Because this analysis shows association rather than direction, both GATAD2B-to-partner and partner-to-GATAD2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ATM grouped by GATAD2B-low versus GATAD2B-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GATAD2B→partner) and Y-score (partner→GATAD2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ATM →	-0.587	-3.571	<.001	.002	3	2
UCEC	Caspase-7-cleavedD198 →	+0.912	+2.926	<.001	<.001	3	2
UCEC	14-3-3_beta →	-0.091	-2.088	.011	.016	3	1
UCEC	eEF2 →	+0.294	+2.321	.022	.033	3	1
UCEC	eIF4E →	+0.184	+2.321	.015	.001	3	1
UCEC	A-Raf_pS299 →	-0.140	-2.000	.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

ATM by GATAD2B expression — UCEC

Explore this box plot interactively →