GATAD2B

Across TCGA cell cohorts, GATAD2B mutation is significantly associated with the RNA expression of many other genes, with 259 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GATAD2B-associated genes across cancer lineages are ESS2, SRRD, and CCDC134. Each is linked with GATAD2B in more than 1 cancer types. Because this analysis shows association rather than direction, both GATAD2B-to-partner and partner-to-GATAD2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ESS2 grouped by GATAD2B-low versus GATAD2B-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GATAD2B→partner) and Y-score (partner→GATAD2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ESS2 →	+0.517	+3.169	.006	.009	3	1
LARGE_INTESTINE	SRRD →	+0.720	+3.169	.002	.006	3	1
LARGE_INTESTINE	CCDC134 →	+0.706	+3.131	.003	.008	3	1
LARGE_INTESTINE	POLDIP3 →	+0.607	+3.502	.001	.001	3	1
LARGE_INTESTINE	PPP6R2 →	+0.577	+2.451	.006	.009	3	1
LARGE_INTESTINE	HMGXB4 →	+0.649	+3.526	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 259 associations by consensus.

ESS2 by GATAD2B expression — LARGE_INTESTINE

Explore this box plot interactively →