GATA6

Across TCGA patient cohorts, GATA6 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,188 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GATA6-associated proteins across cancer lineages are FRZB, HSPB6, and OLFML1. Each is linked with GATA6 in more than 6 cancer types. Because this analysis shows association rather than direction, both GATA6-to-partner and partner-to-GATA6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GATA6 versus FRZB in CCRCC, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GATA6→partner) and Y-score (partner→GATA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	FRZB →	+0.743	+0.533	<.001	<.001	3	7
CCRCC	HSPB6 →	+1.250	+0.612	<.001	<.001	3	6
CCRCC	OLFML1 →	+1.274	+0.704	<.001	<.001	3	6
BRCA	RSU1 →	+0.423	+0.715	<.001	.007	3	6
BRCA	CDC42EP5 →	+0.559	+0.577	<.001	<.001	3	6
GBM	COL14A1 →	+1.286	+0.646	<.001	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,188 associations by consensus.

GATA6 vs FRZB — CCRCC

Explore this scatter interactively →