GATA6

Across TCGA cell cohorts, GATA6 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,173 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GATA6-associated GO terms across cancer lineages are Regulation of antimicrobial humoral response, Sebaceous gland development, and G1 to G0 transition involved in cell differentiation. Each is linked with GATA6 in more than 12 cancer types. Because this analysis shows association rather than direction, both GATA6-to-partner and partner-to-GATA6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of antimicrobial humoral response grouped by GATA6-low versus GATA6-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GATA6→partner) and Y-score (partner→GATA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of antimicrobial humoral response →	+1.432	+2.233	<.001	<.001	3	13
OVARY	Sebaceous gland development →	+1.500	+2.433	<.001	<.001	3	13
URINARY_TRACT	G1 to G0 transition involved in cell differentiation →	+1.043	+1.110	<.001	<.001	3	10
KIDNEY	Response to mechanical stimulus →	+0.075	+1.006	.002	.003	3	9
BONE	Regulation of epithelial to mesenchymal transition →	+0.108	+1.762	.002	<.001	3	9
BONE	Viral process →	+0.070	+1.191	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,173 associations by consensus.

Regulation of antimicrobial humoral response by GATA6 expression — STOMACH

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