GATA2

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, GATA2 mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated GATA2 data layer compared with 25 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher GATA2 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated GATA2 expression acts as an unfavorable survival marker.

UCEC are the cancer types where GATA2 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECOSMedianII,III,IV0.6391.000.0344view →
Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

GATA2–UCEC (OS)

Kaplan–Meier survival curve for GATA2 mass-spec protein-high vs -low samples in UCEC.

Open the UCEC breakdown →

Exploration