GATA2

Across TCGA patient cohorts, GATA2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,832 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GATA2-associated genes across cancer lineages are IL1R1, HTR7, and SVEP1. Each is linked with GATA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GATA2-to-partner and partner-to-GATA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GATA2 versus IL1R1 in BRCA, with a Pearson correlation of 0.76.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GATA2→partner) and Y-score (partner→GATA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	IL1R1 →	+2.308	+1.170	.004	.003	3	2
UCEC	HTR7 →	+0.511	+0.774	<.001	.002	3	2
UCEC	SVEP1 →	+0.916	+0.734	<.001	<.001	3	2
BRCA	MFAP4 →	+2.195	+1.250	.009	.001	3	2
BRCA	NEGR1 →	+1.118	+1.123	<.001	.001	3	2
BRCA	GATA2-AS1 →	+2.864	+1.797	.003	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,832 associations by consensus.

GATA2 vs IL1R1 — BRCA

Explore this scatter interactively →