GATA2

Across TCGA cell cohorts, GATA2 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,081 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GATA2-associated GO terms across cancer lineages are Eosinophil differentiation, Regulation of DNA-templated transcription elongation, and RNA export from nucleus. Each is linked with GATA2 in more than 13 cancer types. Because this analysis shows association rather than direction, both GATA2-to-partner and partner-to-GATA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Eosinophil differentiation grouped by GATA2-low versus GATA2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GATA2→partner) and Y-score (partner→GATA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Eosinophil differentiation →	+1.284	+2.479	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of DNA-templated transcription elongation →	+0.063	+1.372	.001	<.001	3	10
SOFT_TISSUE	RNA export from nucleus →	+0.094	+1.300	<.001	.003	3	10
UPPER_AERODIGESTIVE_TRACT	Nucleic acid catabolic process →	+0.049	+1.267	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Positive regulation of mast cell degranulation →	+0.141	+1.687	<.001	<.001	3	9
BONE	tRNA transcription →	+0.099	+1.407	<.001	.005	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,081 associations by consensus.

Eosinophil differentiation by GATA2 expression — LUNG_SCLC

Explore this box plot interactively →