GATA2-AS1

Across TCGA pan-cancer cohorts, GATA2-AS1 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated GATA2-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher GATA2-AS1 RNA is associated with better overall survival. In most high-consensus cancer types, elevated GATA2-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and BLCA show a favorable association.

KIRC, MESO, and KIRP are the cancer types where GATA2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	OS	Median	All	0.703	0.563	<.001	98	view →
MESO	OS	Median	All	0.266	0.501	<.001	72	view →
KIRP	OS	Median	All	0.824	0.937	.002	72	view →
BLCA	OS	Quartile	All	0.628	0.377	.001	38	view →
ESCA	DFS	Quartile	All	0.372	0.611	.006	36	view →
LIHC	OS	Quartile	All	0.631	0.252	<.001	36	view →
THYM	DFS	Median	II,III,IV	0.893	0.560	<.001	33	view →
READ	OS	Quartile	All	1.000	0.424	.002	33	view →
ACC	OS	Median	All	0.439	0.853	.004	32	view →
THCA	DFS	Tertile	All	0.913	0.732	<.001	30	view →
HNSC	DFS	Quartile	II,III,IV	0.242	0.455	.012	30	view →
COAD	OS	Tertile	III,IV	0.285	0.667	.019	23	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

GATA2-AS1–KIRC (OS)

Open the KIRC breakdown →