Across TCGA pan-cancer cohorts, GAST Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated GAST data layer compared with 17 for mass-spec protein.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where higher GAST Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated GAST expression acts as an unfavorable survival marker.

LIHC are the cancer types where GAST Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	DFS	Median	All	0.086	0.544	<.001	21	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: GAST tumor-vs-normal RNA expression · all GAST data types