Across TCGA patient cohorts, GAST protein abundance is significantly associated with the RNA expression of many other genes, with 133 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GAST-associated genes across cancer lineages are NEK6, RBM18, and DDX31. Each is linked with GAST in more than 1 cancer types. Because this analysis shows association rather than direction, both GAST-to-partner and partner-to-GAST results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAST→partner) and Y-score (partner→GAST) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	NEK6 →	-0.325	-2.316	.009	.004	3	1
PDAC	RBM18 →	-0.403	-1.373	<.001	.007	3	1
PDAC	DDX31 →	-0.386	-1.707	.001	.003	3	1
PDAC	ZNF484 →	-0.453	-1.413	.001	.004	3	1
PDAC	UBAC1 →	-0.264	-1.311	.002	.009	3	1
PDAC	ADAM30 →	+0.043	+1.774	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 133 associations by consensus.

Exploration

GAST survival (RNA) · tumor vs normal (RNA) · all GAST data types