GASK1B

Across TCGA pan-cancer cohorts, GASK1B mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated GASK1B data layer compared with 29 for mass-spec protein and 11 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher GASK1B mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated GASK1B expression acts as an unfavorable survival marker, although some lineages such as CCRCC and LUAD show a favorable association.

PDAC, LSCC, and UCEC are the cancer types where GASK1B mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	OS	Quartile	All	0.244	0.566	.001	58	view →
LSCC	DFS	Tertile	All	0.541	0.845	.001	36	view →
UCEC	OS	Tertile	II,III,IV	0.331	1.000	.007	12	view →
CCRCC	DFS	Tertile	IV	0.861	0.156	.024	6	view →
LUAD	DFS	Median	All	1.000	0.868	.012	5	view →
HNSC	OS	Quartile	III,IV	0.901	0.766	.039	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

GASK1B–PDAC (OS)

Open the PDAC breakdown →