GASK1B

Across TCGA cell cohorts, GASK1B RNA expression is significantly associated with the go_rna of many other GO terms, with 3,731 significant associations in total. BONE shows the largest number of these associations.

The most reproducible GASK1B-associated GO terms across cancer lineages are Negative regulation of epithelial cell proliferation, Negative regulation of actin filament polymerization, and Positive regulation of ER to Golgi vesicle-mediated transport. Each is linked with GASK1B in more than 7 cancer types. Because this analysis shows association rather than direction, both GASK1B-to-partner and partner-to-GASK1B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of epithelial cell proliferation grouped by GASK1B-low versus GASK1B-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GASK1B→partner) and Y-score (partner→GASK1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of epithelial cell proliferation →	+0.101	+2.033	.005	.005	2	8
STOMACH	Negative regulation of actin filament polymerization →	+0.137	+1.967	<.001	<.001	3	7
BONE	Positive regulation of ER to Golgi vesicle-mediated transport →	+0.092	+1.693	<.001	.001	3	7
SOFT_TISSUE	U4 snRNA 3'-end processing →	-0.103	-2.606	.001	<.001	3	7
BONE	Protein targeting to lysosome involved in chaperone-mediated autophagy →	+0.132	+1.421	.002	.008	3	7
UPPER_AERODIGESTIVE_TRACT	Vacuole organization →	+0.061	+1.204	.001	.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,731 associations by consensus.

Negative regulation of epithelial cell proliferation by GASK1B expression — BONE

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