GASK1A

Across TCGA cell cohorts, GASK1A RNA expression is significantly associated with the go_rna of many other GO terms, with 1,132 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GASK1A-associated GO terms across cancer lineages are Negative regulation of myoblast fusion, Negative regulation of mRNA metabolic process, and Adenylate cyclase-modulating G protein-coupled receptor signaling pathway. Each is linked with GASK1A in more than 7 cancer types. Because this analysis shows association rather than direction, both GASK1A-to-partner and partner-to-GASK1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of myoblast fusion grouped by GASK1A-low versus GASK1A-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GASK1A→partner) and Y-score (partner→GASK1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Negative regulation of myoblast fusion →	+0.109	+0.409	.002	.006	3	8
STOMACH	Negative regulation of mRNA metabolic process →	+0.079	+0.667	<.001	.001	3	7
OVARY	Adenylate cyclase-modulating G protein-coupled receptor signaling pathway →	-0.067	-0.740	<.001	<.001	2	7
OESOPHAGUS	Negative regulation of syncytium formation by plasma membrane fusion →	+0.107	+0.409	.002	.006	3	6
LUNG_SCLC	Positive regulation of intracellular estrogen receptor signaling pathway →	+0.129	+0.542	.007	.005	3	6
BREAST	Regulation of myoblast fusion →	+0.083	+0.994	<.001	.008	1	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,132 associations by consensus.

Negative regulation of myoblast fusion by GASK1A expression — OESOPHAGUS

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