GASK1A

Across TCGA cell cohorts, GASK1A mutation is significantly associated with the mutation status of many other genes, with 297 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GASK1A-associated genes across cancer lineages are XPNPEP1, STX2, and WAPL. Each is linked with GASK1A in more than 1 cancer types. Because this analysis shows association rather than direction, both GASK1A-to-partner and partner-to-GASK1A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, XPNPEP1 grouped by GASK1A-low versus GASK1A-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GASK1A→partner) and Y-score (partner→GASK1A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	XPNPEP1 →	+4.321	+5.285	.005	.005	1	2
BLOOD_Leukemia	STX2 →	+4.736	+5.560	.003	.003	1	2
BLOOD_Leukemia	WAPL →	+4.000	+5.050	.008	.008	1	2
BLOOD_Leukemia	CDC14B →	+4.000	+5.050	.008	.008	1	2
LARGE_INTESTINE	ADAMTS5 →	+2.043	+3.693	.009	.009	1	2
LARGE_INTESTINE	KCNC2 →	+2.936	+4.471	.001	.001	1	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 297 associations by consensus.

XPNPEP1 by GASK1A expression — BLOOD_Leukemia

Explore this box plot interactively →