GAS8

Across TCGA patient cohorts, GAS8 protein abundance is significantly associated with the RNA expression of many other genes, with 7,129 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GAS8-associated genes across cancer lineages are CEP126, CFAP300, and CFAP157. Each is linked with GAS8 in more than 3 cancer types. Because this analysis shows association rather than direction, both GAS8-to-partner and partner-to-GAS8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GAS8 versus CEP126 in GBM, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAS8→partner) and Y-score (partner→GAS8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CEP126 →	+1.216	+0.381	.008	.005	3	4
GBM	CFAP300 →	+1.436	+0.423	<.001	.004	3	4
UCEC	CFAP157 →	+1.775	+0.440	<.001	<.001	3	4
UCEC	ZBBX →	+2.145	+0.459	<.001	<.001	3	4
UCEC	ARMC4 →	+1.483	+0.381	<.001	<.001	3	4
UCEC	PPIL6 →	+1.414	+0.500	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,129 associations by consensus.

GAS8 vs CEP126 — GBM

Explore this scatter interactively →