GAS8

Across TCGA cell cohorts, GAS8 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,604 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GAS8-associated GO terms across cancer lineages are Sperm motility, Flagellated sperm motility, and Negative regulation of myoblast fusion. Each is linked with GAS8 in more than 14 cancer types. Because this analysis shows association rather than direction, both GAS8-to-partner and partner-to-GAS8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sperm motility grouped by GAS8-low versus GAS8-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GAS8→partner) and Y-score (partner→GAS8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Sperm motility →	-0.097	-0.737	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Flagellated sperm motility →	-0.097	-0.737	<.001	<.001	3	15
KIDNEY	Negative regulation of myoblast fusion →	+0.113	+1.210	.001	.009	3	14
URINARY_TRACT	Negative regulation of syncytium formation by plasma membrane fusion →	+0.111	+1.154	<.001	.008	3	14
BONE	Negative regulation of mRNA splicing, via spliceosome →	+0.106	+2.146	<.001	<.001	3	13
BONE	Negative regulation of mRNA processing →	+0.099	+2.146	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,604 associations by consensus.

Sperm motility by GAS8 expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →