GAS7

Across TCGA pan-cancer cohorts, GAS7 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated GAS7 data layer compared with 27 for mass-spec protein and 12 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher GAS7 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated GAS7 expression acts as an unfavorable survival marker, although some lineages such as LUAD and PDAC show a favorable association.

CCRCC, LUAD, and UCEC are the cancer types where GAS7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	III,IV	0.740	1.000	.006	24	view →
LUAD	DFS	Quartile	All	0.842	0.468	.003	9	view →
UCEC	OS	Median	II,III,IV	0.647	1.000	.017	8	view →
HNSC	OS	Median	II,III,IV	0.952	1.000	.016	5	view →
PDAC	DFS	Quartile	II,III,IV	0.502	0.288	.040	4	view →
LSCC	DFS	Quartile	II,III,IV	0.635	0.939	.030	3	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

GAS7–CCRCC (DFS)

Open the CCRCC breakdown →