GAS7

Across TCGA patient cohorts, GAS7 protein abundance is significantly associated with the RNA expression of many other genes, with 19,754 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GAS7-associated genes across cancer lineages are ASPA, PDE1B, and ABCA6. Each is linked with GAS7 in more than 7 cancer types. Because this analysis shows association rather than direction, both GAS7-to-partner and partner-to-GAS7 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GAS7 versus ASPA in GBM, with a Pearson correlation of 0.42.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAS7→partner) and Y-score (partner→GAS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	ASPA →	+1.015	+0.436	<.001	<.001	3	8
BRCA	PDE1B →	+0.626	+0.538	<.001	<.001	3	8
OV	ABCA6 →	+1.312	+0.765	.001	.005	3	8
OV	INMT →	+1.814	+0.821	<.001	.002	3	8
BRCA	IFFO1 →	+0.781	+0.563	<.001	<.001	3	8
COAD	KCNMB1 →	+1.037	+0.491	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,754 associations by consensus.

GAS7 vs ASPA — GBM

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