GAS7

Across TCGA cell cohorts, GAS7 mutation is significantly associated with the RNA expression of many other genes, with 493 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GAS7-associated genes across cancer lineages are SNTG2, DDHD1, and PPP4R3A. Each is linked with GAS7 in more than 1 cancer types. Because this analysis shows association rather than direction, both GAS7-to-partner and partner-to-GAS7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNTG2 grouped by GAS7-low versus GAS7-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAS7→partner) and Y-score (partner→GAS7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SNTG2 →	+0.106	+2.274	.004	.005	3	2
LARGE_INTESTINE	DDHD1 →	+0.776	+3.364	.001	.002	3	1
LARGE_INTESTINE	PPP4R3A →	+0.572	+3.451	<.001	.002	3	1
LARGE_INTESTINE	CCP110 →	+0.628	+3.364	.007	.002	3	1
LARGE_INTESTINE	INTS10 →	+0.666	+3.364	.002	.002	3	1
LARGE_INTESTINE	FCGRT →	-2.355	-3.278	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 493 associations by consensus.

SNTG2 by GAS7 expression — LARGE_INTESTINE

Explore this box plot interactively →