GAS2L2

Across TCGA cell cohorts, GAS2L2 mutation is significantly associated with the RNA expression of many other genes, with 494 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GAS2L2-associated genes across cancer lineages are DBX2, HPCAL4, and KSR2. Each is linked with GAS2L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GAS2L2-to-partner and partner-to-GAS2L2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DBX2 grouped by GAS2L2-low versus GAS2L2-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAS2L2→partner) and Y-score (partner→GAS2L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	DBX2 →	+0.006	+5.000	<.001	.006	3	2
LARGE_INTESTINE	HPCAL4 →	+0.338	+3.082	<.001	.007	3	2
LARGE_INTESTINE	KSR2 →	+0.430	+3.502	.002	.001	3	2
BLOOD_Leukemia	TMEM132C →	+0.544	+2.644	<.001	.008	3	2
LARGE_INTESTINE	UFSP2 →	+0.569	+3.082	.001	.007	3	2
LARGE_INTESTINE	TNK1 →	+0.761	+2.386	.003	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 494 associations by consensus.

DBX2 by GAS2L2 expression — PANCREAS

Explore this box plot interactively →