Across TCGA patient cohorts, GAS2L1 mutation is significantly associated with the immune_cell of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GAS2L1-associated genes across cancer lineages are Fibroblasts, CD4+ Tcm, and Endothelial cells. Each is linked with GAS2L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GAS2L1-to-partner and partner-to-GAS2L1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAS2L1→partner) and Y-score (partner→GAS2L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	Fibroblasts →	+0.014	+6.112	.007	.002	3	1
HNSC	CD4+ Tcm →	+0.007	+5.468	<.001	.043	3	1
UCEC	Endothelial cells →	-0.032	-3.161	.049	.019	3	1
UCEC	lymphatic Endothelial cells →	-0.023	-3.427	.021	.005	3	1
UCEC	Mast cells →	+0.018	+2.265	.006	.006	3	1
UCEC	MSC →	-0.195	-2.989	.027	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

Exploration

GAS2L1 survival (RNA) · tumor vs normal (RNA) · all GAS2L1 data types