Across TCGA cell cohorts, GAS2L1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible GAS2L1-associated genes across cancer lineages are FAM205A, VCY1B, and DEFA4. Each is linked with GAS2L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GAS2L1-to-partner and partner-to-GAS2L1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAS2L1→partner) and Y-score (partner→GAS2L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	FAM205A →	+0.019	+3.766	.001	.004	3	1
BREAST	VCY1B →	+1.590	+4.421	<.001	.004	3	1
BREAST	DEFA4 →	+0.035	+4.781	<.001	.003	3	1
BREAST	DEFB125 →	+0.028	+5.312	<.001	<.001	3	1
LARGE_INTESTINE	TKTL2 →	+0.046	+3.187	<.001	.006	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

GAS2L1 survival (RNA) · tumor vs normal (RNA) · all GAS2L1 data types