GAS2

Across TCGA patient cohorts, GAS2 protein abundance is significantly associated with the RNA expression of many other genes, with 4,616 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GAS2-associated genes across cancer lineages are TRIM29, GJB2, and AHNAK2. Each is linked with GAS2 in more than 3 cancer types. Because this analysis shows association rather than direction, both GAS2-to-partner and partner-to-GAS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GAS2 versus TRIM29 in LSCC, with a Pearson correlation of -0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAS2→partner) and Y-score (partner→GAS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	TRIM29 →	-1.950	-1.170	.007	.002	3	4
LSCC	GJB2 →	-2.239	-1.297	<.001	.007	3	3
UCEC	AHNAK2 →	-1.431	-0.630	.002	.001	3	3
LUAD	FAM220A →	-0.454	-0.550	<.001	.001	3	3
PDAC	CLPS →	+4.898	+0.448	<.001	<.001	3	2
HNSC	A2ML1-AS1 →	-1.444	-1.136	.004	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,616 associations by consensus.

GAS2 vs TRIM29 — LSCC

Explore this scatter interactively →