GAS2

Across TCGA patient cohorts, GAS2 protein abundance is significantly associated with the protein abundance of many other proteins, with 7,635 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GAS2-associated proteins across cancer lineages are GAS2_S282, FRAS1, and KRT19_S395. Each is linked with GAS2 in more than 5 cancer types. Because this analysis shows association rather than direction, both GAS2-to-partner and partner-to-GAS2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GAS2 versus GAS2_S282 in LSCC, with a Pearson correlation of 0.92.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GAS2→partner) and Y-score (partner→GAS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	GAS2_S282 →	+3.200	+2.049	.002	.001	2	6
PDAC	FRAS1 →	+0.828	+0.516	<.001	<.001	3	3
BRCA	KRT19_S395 →	-1.037	-2.016	<.001	<.001	3	3
PDAC	PKM →	-0.372	-0.435	<.001	<.001	3	3
PDAC	ARGLU1_S77 →	-0.532	-0.460	<.001	<.001	3	2
CCRCC	ACADSB →	+0.558	+0.643	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,635 associations by consensus.

GAS2 vs GAS2_S282 — LSCC

Explore this scatter interactively →