GAS2

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, GAS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,727 significant associations in total. LIVER shows the largest number of these associations.

The most reproducible GAS2-associated GO terms across cancer lineages are Establishment of vesicle localization, Promoter clearance during DNA-templated transcription, and RNA polymerase II promoter clearance. Each is linked with GAS2 in more than 7 cancer types. Because this analysis shows association rather than direction, both GAS2-to-partner and partner-to-GAS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Establishment of vesicle localization grouped by GAS2-low versus GAS2-high in BLOOD_Leukemia.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GAS2→partner) and Y-score (partner→GAS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LeukemiaEstablishment of vesicle localization →+0.026+1.029<.001<.00138
LIVERPromoter clearance during DNA-templated transcription →+0.136+2.673<.001<.00137
LIVERRNA polymerase II promoter clearance →+0.136+2.673<.001<.00137
LUNG_SCLCCytoplasmic translation →+0.077+1.932.001<.00137
OVARYRespiratory electron transport chain →+0.083+0.510<.001<.00137
UPPER_AERODIGESTIVE_TRACTRegulation of myoblast fusion →+0.118+0.669<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,727 associations by consensus.

Establishment of vesicle localization by GAS2 expression — BLOOD_Leukemia

Box plot of Establishment of vesicle localization in GAS2-low vs GAS2-high samples in BLOOD_Leukemia.

Explore this box plot interactively →

Exploration