GAS2

Across TCGA cell cohorts, GAS2 mutation is significantly associated with the drug of many other genes, with 12 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GAS2-associated genes across cancer lineages are BDF00022089a, PRT062607, and Oxaliplatin. Each is linked with GAS2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GAS2-to-partner and partner-to-GAS2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, BDF00022089a grouped by GAS2-low versus GAS2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAS2→partner) and Y-score (partner→GAS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	BDF00022089a →	+0.312	+2.649	.045	.046	3	1
LARGE_INTESTINE	PRT062607 →	+0.553	+2.769	.028	.040	3	1
LARGE_INTESTINE	Oxaliplatin →	+0.528	+2.678	.046	.037	3	1
LARGE_INTESTINE	GSK2801 →	+0.475	+2.678	.002	.037	2	1
LARGE_INTESTINE	Mirin →	+0.388	+2.646	.041	.047	1	1
LARGE_INTESTINE	Niraparib →	+0.499	+2.646	.004	.047	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 12 associations by consensus.

BDF00022089a by GAS2 expression — LARGE_INTESTINE

Explore this box plot interactively →