GAS1

Across TCGA patient cohorts, GAS1 protein abundance is significantly associated with the RNA expression of many other genes, with 10,222 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GAS1-associated genes across cancer lineages are CCN4, SERPINF1, and ANGPTL2. Each is linked with GAS1 in more than 4 cancer types. Because this analysis shows association rather than direction, both GAS1-to-partner and partner-to-GAS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GAS1 versus CCN4 in BRCA, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAS1→partner) and Y-score (partner→GAS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CCN4 →	+1.234	+0.696	<.001	<.001	3	5
PDAC	SERPINF1 →	+1.338	+1.171	<.001	.003	3	5
BRCA	ANGPTL2 →	+1.535	+1.137	<.001	<.001	3	5
OV	SFRP2 →	+2.866	+0.649	<.001	<.001	3	5
BRCA	COL6A3 →	+2.155	+1.269	<.001	<.001	3	5
PDAC	CLMP →	+1.786	+1.571	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,222 associations by consensus.

GAS1 vs CCN4 — BRCA

Explore this scatter interactively →