GART

Across TCGA cell cohorts, GART RNA expression is significantly associated with the go_rna of many other GO terms, with 4,507 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GART-associated GO terms across cancer lineages are 'de novo' IMP biosynthetic process, Nucleolar large rRNA transcription by RNA polymerase I, and DNA-templated DNA replication. Each is linked with GART in more than 16 cancer types. Because this analysis shows association rather than direction, both GART-to-partner and partner-to-GART results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 'de novo' IMP biosynthetic process grouped by GART-low versus GART-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GART→partner) and Y-score (partner→GART) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	'de novo' IMP biosynthetic process →	+0.210	+0.945	<.001	<.001	3	17
OESOPHAGUS	Nucleolar large rRNA transcription by RNA polymerase I →	+0.119	+0.872	.004	.001	3	16
UPPER_AERODIGESTIVE_TRACT	DNA-templated DNA replication →	+0.135	+1.123	<.001	<.001	3	16
PANCREAS	Transcription initiation at RNA polymerase I promoter →	+0.128	+1.185	<.001	<.001	3	16
BONE	DNA strand elongation →	+0.177	+0.883	<.001	<.001	3	16
BONE	Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →	+0.154	+0.834	<.001	.005	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,507 associations by consensus.

'de novo' IMP biosynthetic process by GART expression — BONE

Explore this box plot interactively →