GARS1

Across TCGA cell cohorts, GARS1 mutation is significantly associated with the drug of many other genes, with 14 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GARS1-associated genes across cancer lineages are GSK2110183B, 630600, and AT7867. Each is linked with GARS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GARS1-to-partner and partner-to-GARS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GSK2110183B grouped by GARS1-low versus GARS1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GARS1→partner) and Y-score (partner→GARS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	GSK2110183B →	+0.782	+2.649	.009	.046	3	1
LARGE_INTESTINE	630600 →	+0.685	+2.649	.027	.046	3	1
LARGE_INTESTINE	AT7867 →	+0.534	+2.652	.026	.045	3	1
LARGE_INTESTINE	kb NB 142-70 →	+0.501	+2.652	.034	.045	3	1
LARGE_INTESTINE	GSK2276186C →	+0.517	+2.649	.025	.046	2	1
LARGE_INTESTINE	50869 →	+0.464	+2.649	.028	.046	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 14 associations by consensus.

GSK2110183B by GARS1 expression — LARGE_INTESTINE

Explore this box plot interactively →