Across TCGA pan-cancer cohorts, GARS1-DT Mutation is linked to patient survival in 1 of 34 cancer types, making it a survival-associated GARS1-DT data layer compared with 28 for mass-spec protein.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher GARS1-DT Mutation is associated with worse overall survival. In most high-consensus cancer types, elevated GARS1-DT expression acts as an unfavorable survival marker.

CESC are the cancer types where GARS1-DT Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	OS	Median	II,III,IV	0.121	0.829	<.001	48	view →

Pink = unfavorable, green = favorable. Showing the 1 strongest of 1 lineages.

Exploration

Same gene, other analysis: GARS1-DT tumor-vs-normal RNA expression · all GARS1-DT data types