GARRE1

Across TCGA cell cohorts, GARRE1 mutation is significantly associated with the RNA expression of many other genes, with 428 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GARRE1-associated genes across cancer lineages are XKR4, CCR6, and XPNPEP2. Each is linked with GARRE1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GARRE1-to-partner and partner-to-GARRE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, XKR4 grouped by GARRE1-low versus GARRE1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GARRE1→partner) and Y-score (partner→GARRE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	XKR4 →	+0.936	+4.038	<.001	.002	3	2
PANCREAS	CCR6 →	+0.666	+4.209	<.001	.002	3	1
PANCREAS	XPNPEP2 →	+0.032	+3.426	<.001	.003	3	1
PANCREAS	UGT2A3 →	+1.056	+4.451	<.001	<.001	3	1
PANCREAS	GC →	+1.071	+3.652	.003	.001	3	1
URINARY_TRACT	DTHD1 →	+0.056	+5.087	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 428 associations by consensus.

XKR4 by GARRE1 expression — BLOOD_Leukemia

Explore this box plot interactively →