GAREM2

Across TCGA cell cohorts, GAREM2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,646 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GAREM2-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Positive regulation of DNA repair, and Renal vesicle formation. Each is linked with GAREM2 in more than 13 cancer types. Because this analysis shows association rather than direction, both GAREM2-to-partner and partner-to-GAREM2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by GAREM2-low versus GAREM2-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GAREM2→partner) and Y-score (partner→GAREM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Epigenetic regulation of gene expression →	+0.065	+1.323	<.001	.002	3	14
SOFT_TISSUE	Positive regulation of DNA repair →	+0.075	+1.061	<.001	.001	3	13
LIVER	Renal vesicle formation →	+1.466	+1.251	<.001	<.001	2	14
LIVER	Metanephric renal vesicle formation →	+1.466	+1.251	<.001	<.001	2	14
STOMACH	DNA-templated transcription initiation →	+0.058	+1.281	<.001	.002	3	13
OVARY	Negative regulation of gene expression, epigenetic →	+0.072	+1.030	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,646 associations by consensus.

Epigenetic regulation of gene expression by GAREM2 expression — LUNG_SCLC

Explore this box plot interactively →