GAREM1

Across TCGA cell cohorts, GAREM1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,038 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible GAREM1-associated GO terms across cancer lineages are Copper ion export, Negative regulation of CD8-positive, alpha-beta T cell differentiation, and Negative regulation of NK T cell activation. Each is linked with GAREM1 in more than 9 cancer types. Because this analysis shows association rather than direction, both GAREM1-to-partner and partner-to-GAREM1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Copper ion export grouped by GAREM1-low versus GAREM1-high in LARGE_INTESTINE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GAREM1→partner) and Y-score (partner→GAREM1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	Copper ion export →	-0.118	-0.625	<.001	<.001	3	10
BREAST	Negative regulation of CD8-positive, alpha-beta T cell differentiation →	+0.202	+0.779	<.001	.001	3	9
LIVER	Negative regulation of NK T cell activation →	+0.201	+1.262	.009	.007	3	8
URINARY_TRACT	3'-UTR-mediated mRNA destabilization →	+0.179	+1.365	<.001	.001	3	8
URINARY_TRACT	Bile acid and bile salt transport →	+0.121	+1.212	.006	.006	3	8
URINARY_TRACT	Negative regulation of endothelial cell differentiation →	+0.285	+1.625	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,038 associations by consensus.

Copper ion export by GAREM1 expression — LARGE_INTESTINE

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