GAR1

Across TCGA patient cohorts, GAR1 mutation is significantly associated with the RNA expression of many other genes, with 1,835 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GAR1-associated genes across cancer lineages are MIR607, MTND2P30, and MTND5P29. Each is linked with GAR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GAR1-to-partner and partner-to-GAR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MIR607 grouped by GAR1-low versus GAR1-high in CESC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAR1→partner) and Y-score (partner→GAR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CESC	MIR607 →	+0.228	+5.569	<.001	.002	3	3
SKCM	MTND2P30 →	+0.121	+5.513	<.001	.004	3	2
CESC	MTND5P29 →	+0.031	+4.812	<.001	.006	3	1
CESC	OR2AI1P →	+0.029	+4.669	.001	.007	3	1
CESC	TRBV26 →	+0.131	+5.342	<.001	.002	3	1
CESC	C1GALT1P2 →	+0.055	+4.934	<.001	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,835 associations by consensus.

MIR607 by GAR1 expression — CESC

Explore this box plot interactively →