GAR1

Across TCGA cell cohorts, GAR1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,000 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GAR1-associated GO terms across cancer lineages are snoRNA guided rRNA pseudouridine synthesis, U1 snRNA 3'-end processing, and U5 snRNA 3'-end processing. Each is linked with GAR1 in more than 19 cancer types. Because this analysis shows association rather than direction, both GAR1-to-partner and partner-to-GAR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, snoRNA guided rRNA pseudouridine synthesis grouped by GAR1-low versus GAR1-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GAR1→partner) and Y-score (partner→GAR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	snoRNA guided rRNA pseudouridine synthesis →	+0.125	+0.767	<.001	<.001	3	20
LUNG_NSCLC_LUSC	U1 snRNA 3'-end processing →	+0.132	+0.946	.001	.001	3	16
LUNG_NSCLC_LUSC	U5 snRNA 3'-end processing →	+0.132	+0.946	.001	.001	3	16
URINARY_TRACT	Protein localization to kinetochore →	+0.154	+0.779	<.001	<.001	3	16
BLOOD_Lymphoma	Maturation of SSU-rRNA →	+0.122	+0.813	<.001	<.001	3	15
PANCREAS	DAMP biosynthetic process →	+0.144	+0.773	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,000 associations by consensus.

snoRNA guided rRNA pseudouridine synthesis by GAR1 expression — SKIN

Explore this box plot interactively →