GAPVD1

Across TCGA pan-cancer cohorts, GAPVD1 mass-spec protein is linked to patient survival in 6 of 34 cancer types, making it a survival-associated GAPVD1 data layer compared with 22 for mass-spec protein and 9 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher GAPVD1 mass-spec protein is associated with worse disease-free survival. In most high-consensus cancer types, elevated GAPVD1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and CCRCC show a favorable association.

PDAC, COAD, and UCEC are the cancer types where GAPVD1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Quartile	All	0.277	0.556	<.001	39	view →
COAD	DFS	Median	All	0.913	1.000	.007	36	view →
UCEC	OS	Quartile	All	1.000	0.881	.031	12	view →
CCRCC	DFS	Tertile	II,III,IV	1.000	0.277	.016	10	view →
HNSC	DFS	Median	II,III,IV	0.984	0.907	.036	2	view →
GBM	DFS	Median	All	0.592	0.747	.044	1	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

GAPVD1–PDAC (DFS)

Open the PDAC breakdown →