GAPVD1

Across TCGA patient cohorts, GAPVD1 mutation is significantly associated with the total protein of many other genes, with 53 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GAPVD1-associated genes across cancer lineages are Stathmin, PCNA, and CD31. Each is linked with GAPVD1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GAPVD1-to-partner and partner-to-GAPVD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Stathmin grouped by GAPVD1-low versus GAPVD1-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAPVD1→partner) and Y-score (partner→GAPVD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Stathmin →	+0.146	+3.012	.043	.018	3	3
LUSC	PCNA →	+0.329	+2.816	.005	.036	3	2
COAD	CD31 →	+0.180	+2.178	.025	.035	3	2
COAD	Cyclin-E1 →	+0.315	+2.178	.007	.035	3	2
UCEC	MEK1 →	+0.296	+1.540	.003	.001	3	2
UCEC	MSH6 →	-0.229	-1.362	.011	.031	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 53 associations by consensus.

Stathmin by GAPVD1 expression — COAD

Explore this box plot interactively →