GAPVD1

Across TCGA cell cohorts, GAPVD1 mutation is significantly associated with the RNA expression of many other genes, with 29 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GAPVD1-associated genes across cancer lineages are GPHB5, DAZ4, and NPY. Each is linked with GAPVD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GAPVD1-to-partner and partner-to-GAPVD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, GPHB5 grouped by GAPVD1-low versus GAPVD1-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAPVD1→partner) and Y-score (partner→GAPVD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	GPHB5 →	+0.058	+5.000	<.001	.006	3	2
LARGE_INTESTINE	DAZ4 →	+0.109	+2.977	.008	.006	3	2
SOFT_TISSUE	NPY →	+2.013	+3.409	.001	.009	3	1
SOFT_TISSUE	CDHR4 →	+0.392	+3.373	<.001	.007	3	1
SOFT_TISSUE	MAGEA9B →	+1.339	+3.442	.002	.005	3	1
PANCREAS	TSHB →	+0.055	+5.000	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

GPHB5 by GAPVD1 expression — PANCREAS

Explore this box plot interactively →