GAPDHS

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GAPDHS RNA expression is significantly associated with the protein abundance of many other proteins, with 10,571 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GAPDHS-associated proteins across cancer lineages are QTRT1, GTF2I, and MBD3. Each is linked with GAPDHS in more than 3 cancer types. Because this analysis shows association rather than direction, both GAPDHS-to-partner and partner-to-GAPDHS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GAPDHS versus QTRT1 in GBM, with a Pearson correlation of 0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GAPDHS→partner) and Y-score (partner→GAPDHS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMQTRT1 →+0.397+0.404<.001<.00134
GBMGTF2I →+0.351+0.394.003<.00134
HNSCMBD3 →+0.552+0.519<.001<.00134
LSCCBPTF →+0.284+0.418<.001<.00134
LUADEEF2_S502 →-0.667-0.316<.001.00134
GBMKRI1 →+0.516+0.469<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,571 associations by consensus.

GAPDHS vs QTRT1 — GBM

Per-sample scatter of GAPDHS vs QTRT1 in GBM (Pearson r = 0.41).

Explore this scatter interactively →

Exploration