GAPDHS

Across TCGA patient cohorts, GAPDHS protein abundance is significantly associated with the RNA expression of many other genes, with 1,603 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GAPDHS-associated genes across cancer lineages are KLF4, MIR1-1HG-AS1, and RNU6-724P. Each is linked with GAPDHS in more than 1 cancer types. Because this analysis shows association rather than direction, both GAPDHS-to-partner and partner-to-GAPDHS results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GAPDHS versus KLF4 in LUAD, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAPDHS→partner) and Y-score (partner→GAPDHS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	KLF4 →	+1.683	+1.100	<.001	.001	3	2
OV	MIR1-1HG-AS1 →	-0.160	-0.745	.001	.006	3	2
HNSC	RNU6-724P →	-1.318	-0.525	.001	.003	3	2
UCEC	SH3BGRL3 →	+0.833	+0.378	.009	.003	3	1
UCEC	ADAM32 →	-1.706	-0.404	.003	.001	3	1
UCEC	USP17L6P →	-0.280	-0.551	.005	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,603 associations by consensus.

GAPDHS vs KLF4 — LUAD

Explore this scatter interactively →