GAPDHS

Across TCGA cell cohorts, GAPDHS RNA expression is significantly associated with the go_rna of many other GO terms, with 2,018 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GAPDHS-associated GO terms across cancer lineages are Regulation of tumor necrosis factor superfamily cytokine production, Viral gene expression, and Positive regulation of postsynaptic membrane organization. Each is linked with GAPDHS in more than 4 cancer types. Because this analysis shows association rather than direction, both GAPDHS-to-partner and partner-to-GAPDHS results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of tumor necrosis factor superfamily cytokine production grouped by GAPDHS-low versus GAPDHS-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GAPDHS→partner) and Y-score (partner→GAPDHS) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of tumor necrosis factor superfamily cytokine production →	+0.065	+0.034	.002	.008	3	5
BREAST	Viral gene expression →	+0.066	+0.035	.004	.007	3	5
SKIN	Positive regulation of postsynaptic membrane organization →	+0.137	+1.321	<.001	.006	3	5
SKIN	Positive regulation of AMPA glutamate receptor clustering →	+0.137	+1.321	<.001	.006	3	5
UPPER_AERODIGESTIVE_TRACT	Negative regulation of hyaluronan biosynthetic process →	+0.140	+0.040	<.001	.007	3	4
UPPER_AERODIGESTIVE_TRACT	Regulation of intralumenal vesicle formation →	+0.100	+0.057	<.001	.004	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,018 associations by consensus.

Regulation of tumor necrosis factor superfamily cytokine production by GAPDHS expression — BREAST

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