GAPDHP61

Across TCGA pan-cancer cohorts, GAPDHP61 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated GAPDHP61 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher GAPDHP61 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated GAPDHP61 expression acts as an unfavorable survival marker, although some lineages such as LUSC and UCS show a favorable association.

KICH, MESO, and LUSC are the cancer types where GAPDHP61 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Median	II,III,IV	0.622	1.000	<.001	97	view →
MESO	OS	Median	All	0.428	0.644	<.001	75	view →
LUSC	OS	Tertile	All	0.752	0.597	.002	45	view →
UCS	DFS	Median	IV	0.952	0.367	.001	36	view →
LIHC	DFS	Quartile	All	0.393	0.614	<.001	34	view →
ACC	OS	Tertile	II,III,IV	0.730	0.919	.009	26	view →
THYM	DFS	Median	III,IV	0.503	1.000	.011	15	view →
SARC	DFS	Tertile	All	0.505	0.746	.002	15	view →
DLBC	DFS	Median	III,IV	1.000	0.525	.013	12	view →
LAML	DFS	Quartile	All	0.816	0.442	.013	12	view →
READ	DFS	Median	III,IV	0.618	0.361	.019	9	view →
KIRP	OS	Median	All	0.574	0.824	.010	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

GAPDHP61–KICH (OS)

Open the KICH breakdown →