Across TCGA pan-cancer cohorts, GAPDHP54 RNA differs between tumor and matched normal tissue in 2 of 18 cancer types tested, making tumor–normal expression one of GAPDHP54’s most consistent transcriptional readouts.
The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where GAPDHP54 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GAPDHP54 is over-expressed in tumor.
UCEC and LUSC are the cancer types where GAPDHP54 tumor–normal differential expression is most reproducible.