GAPDHP53

Across TCGA patient cohorts, GAPDHP53 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,502 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GAPDHP53-associated GO terms across cancer lineages are Negative regulation of binding, Regulation of circadian rhythm, and Regulation of double-strand break repair. Each is linked with GAPDHP53 in more than 5 cancer types. Because this analysis shows association rather than direction, both GAPDHP53-to-partner and partner-to-GAPDHP53 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of binding grouped by GAPDHP53-low versus GAPDHP53-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GAPDHP53→partner) and Y-score (partner→GAPDHP53) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Negative regulation of binding →	+0.107	+0.043	<.001	.007	3	6
STAD	Regulation of circadian rhythm →	+0.091	+0.051	<.001	.002	3	5
STAD	Regulation of double-strand break repair →	+0.104	+0.043	<.001	.005	3	5
STAD	Negative regulation of apoptotic signaling pathway →	+0.122	+0.050	<.001	.003	3	5
STAD	Nucleobase-containing compound transport →	+0.119	+0.027	<.001	.001	3	5
STAD	Methylation →	+0.104	+0.045	<.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,502 associations by consensus.

Negative regulation of binding by GAPDHP53 expression — STAD

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