GAPDHP50

Across TCGA pan-cancer cohorts, GAPDHP50 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of GAPDHP50’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where GAPDHP50 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GAPDHP50 is over-expressed in tumor.

HNSC, KIRC, and LUSC are the cancer types where GAPDHP50 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GAPDHP50 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	Male	III,IV	+0.037	.013	5	view →
KIRC	Male	II,III,IV	+0.010	.021	5	view →
LUSC	All	All	+0.012	.019	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

GAPDHP50–HNSC

Open the HNSC breakdown →