GAPDHP32

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GAPDHP32 mutation is significantly associated with the RNA expression of many other genes, with 16 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GAPDHP32-associated genes across cancer lineages are AQP7P4, RNU6-508P, and MRPL32P1. Each is linked with GAPDHP32 in more than 1 cancer types. Because this analysis shows association rather than direction, both GAPDHP32-to-partner and partner-to-GAPDHP32 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAPDHP32→partner) and Y-score (partner→GAPDHP32) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECAQP7P4 →+0.228+6.027<.001.00231
UCECRNU6-508P →+1.414+6.453<.001.00131
UCECMRPL32P1 →+0.587+5.694<.001.00331
UCECRNU2-14P →+1.103+5.133<.001.00831
UCECPGBD4P5 →+0.328+5.852<.001.00331
UCECMTND6P15 →+0.299+5.242<.001.00731
Each partner links to its Q-omics profile. Showing the 6 strongest of 16 associations by consensus.

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