GAP43

Across TCGA patient cohorts, GAP43 protein abundance is significantly associated with the RNA expression of many other genes, with 11,374 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible GAP43-associated genes across cancer lineages are TGFB3, NAP1L3, and DACT3. Each is linked with GAP43 in more than 6 cancer types. Because this analysis shows association rather than direction, both GAP43-to-partner and partner-to-GAP43 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GAP43 versus TGFB3 in BRCA, with a Pearson correlation of 0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAP43→partner) and Y-score (partner→GAP43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TGFB3 →	+1.555	+1.077	<.001	<.001	3	7
BRCA	NAP1L3 →	+1.229	+1.292	<.001	<.001	3	7
BRCA	DACT3 →	+1.069	+1.159	<.001	<.001	3	7
COAD	SFRP4 →	+2.560	+0.894	<.001	<.001	3	6
BRCA	ASPN →	+2.237	+0.864	<.001	<.001	3	6
BRCA	CPE →	+1.732	+0.904	<.001	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,374 associations by consensus.

GAP43 vs TGFB3 — BRCA

Explore this scatter interactively →