GAP43

Across TCGA cell cohorts, GAP43 mutation is significantly associated with the drug of many other genes, with 24 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GAP43-associated genes across cancer lineages are SGC-CBP30, CZC24832, and Dactinomycin. Each is linked with GAP43 in more than 1 cancer types. Because this analysis shows association rather than direction, both GAP43-to-partner and partner-to-GAP43 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SGC-CBP30 grouped by GAP43-low versus GAP43-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GAP43→partner) and Y-score (partner→GAP43) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	SGC-CBP30 →	+0.368	+2.649	.008	.046	3	1
LARGE_INTESTINE	CZC24832 →	+0.344	+2.646	.007	.047	3	1
LARGE_INTESTINE	Dactinomycin →	+0.532	+2.649	.023	.046	3	1
LARGE_INTESTINE	123829 →	+0.695	+2.649	.016	.046	3	1
LARGE_INTESTINE	Elephantin →	+0.408	+2.777	.039	.038	3	1
LARGE_INTESTINE	CX-5461 →	+0.612	+2.652	.038	.045	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

SGC-CBP30 by GAP43 expression — LARGE_INTESTINE

Explore this box plot interactively →