Across TCGA patient cohorts, GANC RNA expression is significantly associated with the protein abundance of many other proteins, with 12,768 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible GANC-associated proteins across cancer lineages are UBR1, DDX21_S71, and SLIRP. Each is linked with GANC in more than 5 cancer types. Because this analysis shows association rather than direction, both GANC-to-partner and partner-to-GANC results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GANC→partner) and Y-score (partner→GANC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	UBR1 →	+0.266	+0.452	<.001	.001	2	6
BRCA	DDX21_S71 →	-1.370	-0.504	<.001	<.001	3	5
LUAD	SLIRP →	-0.443	-0.542	<.001	<.001	3	5
PDAC	TBRG4 →	-0.395	-0.360	<.001	<.001	3	5
LSCC	PYCR2 →	-0.660	-0.573	<.001	<.001	3	5
LSCC	LRPPRC →	-0.394	-0.425	.003	.004	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 12,768 associations by consensus.

Exploration

GANC survival (RNA) · tumor vs normal (RNA) · all GANC data types