Across TCGA patient cohorts, GANC protein abundance is significantly associated with the RNA expression of many other genes, with 3,694 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GANC-associated genes across cancer lineages are E2F1, UBE2S, and NCAPH. Each is linked with GANC in more than 3 cancer types. Because this analysis shows association rather than direction, both GANC-to-partner and partner-to-GANC results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GANC→partner) and Y-score (partner→GANC) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	E2F1 →	-1.044	-0.381	<.001	.002	3	3
OV	UBE2S →	-1.117	-0.671	.001	<.001	3	3
OV	NCAPH →	-1.041	-0.722	<.001	<.001	3	3
OV	TROAP →	-0.958	-0.559	.003	.001	3	3
OV	CDC25C →	-0.940	-0.762	.002	<.001	3	3
OV	RACGAP1 →	-0.850	-0.528	<.001	.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,694 associations by consensus.

Exploration

GANC survival (RNA) · tumor vs normal (RNA) · all GANC data types